Stampfl APJ, Liu Z, Hu J, Sawada K, Takano H, Kohmura Y, Ishikawa T, Lim JH, Je JH, Low CM, Teo A, Tok ES, Tan TW, Ban K, Libedinsky C, Tan FCK, Chen KP, Yang AC, Chuang CC, Chen NY, Shih CT, Lee TK, Yang DN, Lai HC, Shuai HH, Cheng CC, Ching YT, Li CW, Charng CC, Lo CC, Chiang AS, Recur B, Petibois C, Cheng CL, Chen HH, Yang SM, Hwu Y, Rojviriya C, Rugmai S, Rujirawat S, Margaritondo G* (2023) SYNAPSE: An international roadmap to large brain imaging. Physics Reports 999, 1–60. doi.org/10.1016/j.physrep.2022.11.003 (IF: 25.6)
Lin HW, Chen CC, Jhang RY, Chen L, de Belle JS, Tully T, Chiang AS* (2022) CREBB repression of protein synthesis in mushroom body gates long-term memory formation in Drosophila. Proc Natl Acad Sci USA 119, e2211308119. DOI:10.1073/pnas.2211308119 (IF: 12.779)
Yu-Jui Fan*, Han-Yun Hsieh, Yen-Ru Huang, Chieh Tsao, Chia-Ming Lee, Hidetoshi Tahara, Yi-Chun Wu, Horn-Jiunn Sheen* and Bi-Chang Chen* (2022) Development of water refractive index matched microneedle integrating with lightsheet microscopic system for continuous embryonic cell imaging. Lab on a Chip 22, DOI: 10.1039/D1LC00827G (IF: 6.799)
Arjun Ashoka, Ronnie R. Tamming, Aswathy V. Girija, Hope Bretscher, Sachin Dev Verma, Shang-Da Yang, Chih-Hsuan Lu, Justin M. Hodgkiss, David Ritchie, Chong Chen, Charles G. Smith, Christoph Schnedermann, Michael B. Price, Kai Chen & Akshay Rao* (2022) Extracting quantitative dielectric properties from pump-probe spectroscopy. Nat. Commun. 13, DOI: 10.1038/s41467-022-29112-y(IF: 14.919)
Yen-Yu Lin#, Lei-Chi Wang #, Yu-Han Hsieh, Yu-Ling Hung, Yung-An Chen, Yu-Chieh Lin, Yen-Yin Lin, Teh-Ying Chou* (2022) Computer-assisted three-dimensional quantitation of programmed death-ligand 1 in non-small cell lung cancer using tissue clearing technology. J. Transl. Med. 20, DOI: 10.1186/s12967-022-03335-5 (IF: 5.531)
Tzy-Wei Huang, Frank H C Cheng, Ching-Cher Sanders Yan, Yu-Ming Chuang, Chien-Hong Cho, Hung-Cheng Lai, Shih-Feng Shieh, Michael W Y Chan*, Je-Chiang Tsai* (2022 Feb 18) Interplay between ceRNA and Epigenetic Control of microRNA: Modelling Approaches with Application to the Role of Estrogen in Ovarian Cancer. Int J Mol Sci.23, DOI: 10.3390/ijms23042277 (IF: 5.924)
Meng-Hsuan Chiang, Shuk-Man Ho, Hui-Yu Wu, Yu-Chun Lin, Wan-Hua Tsai, Tony Wu, Chih-Ho Lai*, Chia-Lin Wu* (2022) Drosophila Model for Studying Gut Microbiota in Behaviors and Neurodegenerative Diseases. Biomedicines 10, DOI: 10.3390/biomedicines10030596 (IF: 6.081)
Wei Cheng, Yu-Lin Su, Hao-Hsiang Hsu, Ya-Hui Lin, Li-An Chu, Wei-Chen Huang, Yu-Jen Lu, Chi-Shiun Chiang, and Shang-Hsiu Hu* (2022) Rabies Virus Glycoprotein-Mediated Transportation and T Cell Infiltration to Brain Tumor by Magnetoelectric Gold Yarnballs. ACS Nano 16, DOI: 10.1021/acsnano.1c09601 (Cover story) (IF: 15.881)
Guan-Jie Huang, Hao-Yu Cheng, Yu-Lung Tang, Ikuto Hotta, Junichi Takahara, Kung-Hsuan Lin*, Shi-Wei Chu* (2022) Transient Super-/Sub-Linear Nonlinearities in Silicon Nanostructures. Adv. Opt. Mater. 10, DOI: 10.1002/adom.202101711 (Selected as Inside Front Cover for upcoming issue) (IF: 9.926)
Publications(2020-2023)(IF: impact factor >5)
Kuan-Chung Cheng, Chun Hei Antonio Cheung, Hsueh-Cheng Chiang*. (2022) Early Aβ42 Exposure Causes Learning Impairment in Later Life. Aging and Disease 13, DOI: 10.14336/AD.2021.1015(IF: 6.745)
Chen-Ting Hung, Tung-Hung Su, Yen-Ting Chen, Yueh-Feng Wu, You-Tzung Chen, Sung-Jan Lin, Shuei-Liong Lin, Kai-Chien Yang* (2021) Targeting ER protein TXNDC5 in hepatic stellate cell mitigates liver fibrosis by repressing non-canonical TGFβ signaling. Gut Online ahead of print, DOI: 10.1136/gutjnl-2021-325065(IF: 23.059)
Kuan-Chung Cheng, Yu-Luen Hwang, Hsueh-Cheng Chiang*. (2021) The double-edged sword effect of HDAC6 in Aβ toxicities. FASEB J 36, DOI: 10.1096/fj.202101061R(IF: 5.192)
Yi-Ting Wu, Chun-Hui Chang*. (2021) Functional Reuniens and Rhomboid Nuclei are Required for Proper Acquisition and Expression of Cued and Contextual Fear in Trace Fear Conditioning. Int J Neuropsychoph 25, DOI: 10.1093/ijnp/pyab094(IF: 5.176)
Kuan-Chung Cheng, Ying-Hao Chen, Chia-Lin Wu, Wang-Pao Lee, Chun Hei Antonio Cheung, Hsueh-Cheng Chiang*. (2021) Rac1 and Akt exhibit distinct roles in mediating Ab-induced memory damage and learning impairment. Mol Neurobiol 58, DOI: 10.1007/s12035-021-02471-1 (IF: 5.590)
Wang-Pao Lee, Meng-Hsuan Chiang, Li-Yun Chang, Wei-Huan Shyu, Tai-Hsiang Chiu, Tsai-Feng Fu, Tony, Wu, Chia-Lin Wu*. (2021) Serotonin signals modulate mushroom body output neurons for sustaining water-reward long-term memory in Drosophila.Frontiers in Cell and Developmental Biology 9, DOI: 10.3389/fcell.2021.755574(IF: 6.684)
Kuan-Lin Feng, Ju-Yun Weng, Chun-Chao Chen, Mohammed Bin Abubaker, Hsuan-Wen Lin, Ching-Che Charng, J. Steven de Belle, Tim Tully, Cheng-Chang Lien*, Ann-Shyn Chiang*. (2021) Neuropeptide F inhibits dopamine neuron interference of long-term memory consolidation in Drosophila.iScience 24, DOI: doi.org/10.1016/j.isci.2021.103506(IF: 5.458)
Hsuan-Wen Lin#,Chun-Chao Chen#, J. Steven de Belle, Tim Tully*, Ann-Shyn Chiang*. (2021) CREBA and CREBB in two identified neurons gate long-term memory formation in Drosophila.Proc. Natl. Acad. Sci. USA. 118, DOI: 10.1073/pnas.2100624118 (IF: 11.205)
Publications(2020-2023)(IF: impact factor >5)
Ya-Chu Chang, Yu-Xiang Peng, Bo-Hua Yu, Henry C. Chang, Pei-Shin Liang, Ting-Yi Huang, Chao-Jie Shih, Li-An Chu & Tzu-Kang Sang*. (2021) VCP maintains nuclear size by regulating the DNA damage-associated MDC1–p53–autophagy axis in Drosophila.Nat. Commun. 12, DOI: 10.1038/s41467-021-24556-0 (IF: 14.919)
Musa Iyiola Ajibola, Jei-Wei Wu, Wahab Imam Abdulmajeed, Cheng-Chang Lien*. (2021) Hypothalamic Glutamate/GABA Co-transmission Modulates Hippocampal Circuits and Supports Long-term Potentiation. J. Neurosci. Online ahead of print, DOI: 10.1523/JNEUROSCI.0410-21.2021 (IF: 6.167)
Yueh-Chi Wu, Elan D Louis, John Gionco, Ming-Kai Pan, Phyllis L Faust, Sheng-Han Kuo*. Increased Climbing Fiber Lateral Crossings on Purkinje Cell Dendrites in the Cerebellar Hemisphere in Essential Tremor. Mov. Disord. 36, DOI: 10.1002/mds.28502 (IF: 10.388)
Li-An Chu*, Shu-Wei Chang, Wei-Chun Tang, Yu-Ting Tseng, Peilin Chen, Bi-Chang Chen*. (2021) 5D superresolution imaging for a live cell nucleus. Curr Opin Genet Dev. 67, DOI: 10.1016/j.gde.2020.11.005.(IF: 5.578)
Sheng-Kai Liang§, Chia-Chan Hsu§, Hsiang-Lin Song, Yu-Chi Huang, Chun-Wei Kuo, Xiang Yao, Chien-Cheng Li, Hui-Chen Yang, Yu-Ling Hung, Sheng-Yang Chao, Shun-Chi Wu, Feng-Ren Tsai, Jen-Kun Chen, Wei-Neng Liao, Shin-Chin Cheng, Tsui-Chun Tsou & I-Ching Wang*. (2021) FOXM1 is required for small cell lung cancer tumorigenesis and associated with poor clinical prognosis. Oncogene Online ahead of print, DOI: doi.org/10.1038/s41388-021-01895-2.(IF: 9.867)
Geng-Shi Jeng, Meng-Lin Li, MinWoo Kim, Soon Joon Yoon, John J. Pitre Jr, David S. Li, Ivan Pelivanov* & Matthew O’Donnell. (2021) Real-time interleaved spectroscopic photoacoustic and ultrasound (PAUS) scanning with simultaneous fluence compensation and motion correction. Nature Communications 12, DOI: 10.1038/s41467-021-20947-5. (IF: 14.919)
Chih-Lung Chen, Wen-Yen Huang, Eddy Hsi Chun Wang, Kang-Yu Tai, Sung-Jan Lin* (2020) Functional Complexity of hair follicle stem cell niche and therapeutic targeting of niche dysfunction for hair regeneration. Journal of Biomedical Science 14, DOI: DOI: 10.1186/s12929-020-0624-8. (IF: 8.410)
Kentaro Nishida, Gitanjal Deka, Nicholas Isaac Smith, Shi-Wei Chu*, and Katsumasa Fujita* (2020) Nonlinear scattering of near-infrared light for imaging plasmonic nanoparticles in deep tissue. ACS Photonics 7, DOI: 10.1021/acsphotonics.0c00607. (IF: 7.529)
Ming H Hsieh, Yi-Ling Chien, Susan Shur-Fen Gau*, (2021) Mismatch negativity and P3a in drug-naive adults with attention-deficit hyperactivity disorder. Psychol Med. Published Online: 2021 Mar 12, DOI: 10.1017/S0033291720005516. (IF: 7.723)
Hsiang-Yuan Lin, Daniel Kessler, Wen-Yih Isaac Tseng, Susan Shur-Fen Gau* (2021) Increased functional segregation related to the salience network in unaffected siblings of youths with attention-deficit/hyperactivity disorder. Journal of the American Academy of Child and Adolescent Psychiatry 60, DOI: 10.1016/j.jaac.2019.11.012 (IF: 8.829)
Publications(2020-2023)(IF: impact factor >5)
Yu-Chien Huang, Te-Hsin Chen, Jz-Yuan Juo, Shi-Wei Chu, and Chia-Lung Hsieh* (2021) Quantitative imaging of single light-absorbing nanoparticles by widefield interferometric photothermal microscopy. ACS Photonics 8, DOI: 10.1021/acsphotonics.0c01648. (IF: 7.529)
Yu-Ju Chou*, Yi-Han Lu, Yu-Kai Ma, Yu-Shan Su, Tsung-Han Kuo* (2021) The decisive role of subordination in social hierarchy in weanling mice and young children. iScience 24, DOI: 10.1016/j.isci.2021.102073 (IF: 5.458)
Guan-Jye Seng, Wan-Ling Tseng, Yen-Nan Chiu, Wen-Che Tsai, Yu-Yu Wu, Susan Shur-Fen Gau* (2020) Executive functions in youths with autism spectrum disorder and their unaffected siblings. Psychological Medicine 4, DOI: 10.1017/S0033291720001075. (IF: 7.723)
Chi-Shin Wu, Alex R Luedtke, Ekaterina Sadikova, Hui-Ju Tsai, Shih-Cheng Liao, Chen-Chung Liu, Susan Shur-Fen Gau, Tyler J VanderWeele, Ronald C Kessler* (2020) Development and validation of a machine learning individualized treatment rule in first-episode schizophrenia. JAMA Network Open 2, DOI: 10.1001/jamanetworkopen.2019.21660. (IF: 8.483)
Yi-Ling Chien, Chi-Chao Chao, Shao-Wei Wu, Hsueh-Wen Hsueh, Yen-Nan Chiu, Wen-Che Tsai, Susan Shur-Fen Gau*, Sung-Tsang Hsieh* (2020) Small fiber pathology in autism and clinical implications. Neurology 10, DOI: 10.1212/WNL.0000000000010932. (IF: 9.910)
Publications (2010-2019)
Feng KL and Chiang AS* (2019) Forgetting memories through distinct actin remodeling mechanisms Proc Natl Acad Sci USA 116, 20807–20808. (IF: 9.412, 5-Year IF: 10.620)Link
Chu LA*, Lu CH*, Yang SM, Liu YT, Feng KL, Tsai YCh, Chang WK, Wang WC, Chang SW, Chen P, Lee TK, Hwu YK, Chiang AS*, Chen BC* (2019) Rapid single-wavelength lightsheet localization microscopy for clarified tissue. Nature Communications 10: 4762. (IF: 12.121)Link
發明「透化層光定位顯微鏡」，將超解析顯微技術推展到可觀察大組織內任意單一蛋白質分子的定位，為組織生理與病理學研究的革命性突破。繼之前找到記憶神經元(2012 Science 335, 678–685)，我們應用此技術首次可觀察記憶蛋白質在全腦神經突觸的分布，為破解記憶機制的里程碑。新聞稿連結：https://www.nthu.edu.tw/pdf/pdf_157439061376.pdf。
Sung YC, Jin PR, Chu LA, Hsu FF, Wang MR, Chang CC, Chiou SJ, Qiu JT, Gao DY, Lin CC, Chen YS, Hsu YC, Wang J, Wang FN, Yu PL, Chiang AS, Wu Anthony YT, Ko John JS, Lai Charles PK, Lu TT*, Chen Y* (2019) Delivery of nitric oxide with a nanocarrier promotes tumour vessel normalization and potentiates anti-cancer therapies. Nature Nanotechnology 14: 1160-1169. (IF: 31.538)
Hwu Y*, Margaritondo G* and Chiang AS*. (2017). Q&A: Why use synchrotron x-ray tomography for multi-scale connectome mapping? BMC Biology 15: 122, doi: 10.1186/s12915-017-0461-8.(IF: 6.765)
Lo CC*, Chiang AS*. (2016). Toward whole-body connectomics. J Neurosci 36: 11375-11383. (IF: 5.674, 5-Year IF: 6.335) (This review article is based on a Presidential Lecture at the Neuroscience 2016 Annual Meeting)
Shih HW, Wu CL*, Chang SW, Liu TH, Sih-Yu Lai J, Fu TF, Fu CC, Chiang AS*. (2015, Jul). Parallel circuits control temperature preference in Drosophila during ageing. Nature Communications 6: 7775. (IF: 12.121)
Shih CT*, Sporns O, Yuan SL, Su TS, Lin YJ, Chuang CC, Wang TY, Lo CC, Greenspan RJ, Chiang AS*. (2015, Apr). Connectomics-Based Analysis of Information Flow in the Drosophila Brain. Curr Biol 25: 1249-1258. (IF: 9.601, 5-Year IF: 10.174)
Schoofs A, Hückesfeld S, Schlegel P, Miroschnikow A, Bader R, Zeymer M, Spieß R, Chiang AS, Pankratz MJ*. (2014). Selection of motor programs for suppressing food intake and inducing locomotion in the Drosophila brain. PLoS Biol 12: e1001893. (IF:7.076, 5-Year IF: 8.879)
Wu MC, Chu LA, Hsiao PY, Lin YY, Chi CC, Liu TH, Fu CC*, Chiang AS*. (2014). Optogenetic control of selective neural activity in multiple freely moving Drosophila adults. Proc Natl Acad Sci USA 111: 5367-5372. (IF: 9.412, 5-Year IF: 10.620)
Publications (2010-2019)
Wu CL, Shih MF M, Lee PT, Chiang AS*. (2013). An Octopamine–Mushroom Body Circuit Modulates the Formation of Anesthesia-Resistant Memory in Drosophila.Curr Biol 23: 1-9. (IF: 9.601, 5-Year IF: 10.174)
Lin HH, Chu LA, Fu TF, Dickson BJ, Chiang AS*. (2013). Parallel neural pathways mediate CO2 avoidance responses in Drosophila.Science 340: 1338-1341. (IF: 41.846, 5-Year IF: 44.374; this article has been reviewed in the “PERSPECTIVES” of the same Science issue, p1295-1297)
Lin CY, Chuang CC, Hua TE, Chen CC, Dickson BJ, Greenspan RJ, Chiang AS*. (2013). A comprehensive wiring diagram of the protocerebral bridge for visual information processing in the Drosophila brain. Cell Rep 3: 1739-1753. (IF: 8.109, 5-Year IF: 8.817)
Pai TP, Chen CC, Lin HH, Chin AL, Lai JSY, Lee PT, Tully T, Chiang AS*. (2013). Drosophila ORB protein in two mushroom body-output neurons is necessary for long-term memory formation. Proc Natl Acad Sci USA 110: 7898-7903. (IF: 9.412, 5-Year IF: 10.620)
Wu TH, Lu YN, Chuang CL, Wu CL, Chiang AS, Krantz DE, Chang HY. (2013). Loss of vesicular dopamine release precedes tauopathy in degenerative dopaminergic neurons in a Drosophila model expressing human tau. Acta Neuropathol 125: 711-725. (IF: 14.256, 5-Year IF: 16.293)
Dubnau J*, Chiang AS*. (2013). Systems memory consolidation in Drosophila.Curr Opin Neurobiol 23: 84-91. (IF: 6.263, 5-Year IF: 6.208)
Lehnert BP, Baker AE, Gaudry Q, Chiang AS, Wilson RI. (2013). Distinct roles of TRP channels in auditory transduction and amplification in Drosophila.Neuron 77: 115-128. (IF: 14.415, 5-Year IF: 15.999)
Zhou C, Huang H, Kim S, Lin HW, Meng X, Chiang AS, Wang JW, Jiao R, Rao Y. (2012). Molecular genetic analysis of sexual rejection: roles of octopamine and its receptor OAMB in Drosophila courtship conditioning. J Neurosci 32: 14281-14287. (IF: 5.674, 5-Year IF: 6.335)
Chen CC, Wu JK, Lin HW, Pai TP, Fu TF, Wu CL, Tully T, Chiang AS*. (2012). Visualizing long-term memory formation in two neurons of the Drosophila brain. Science 335: 678–685. [101年大學指考試題39-41](IF: 41.846, 5-Year IF: 44.374; cited by 30 articles; this article has been reviewed in the “PERSPECTIVES” of the same Science issue, p664-665; this article has been introduced by the Science Editor in the “EDITOR’S CHOICE” of the Science Signaling 14, ec50)
Lai JSY, Lo SJ, Dickson BJ and Chiang AS*. (2012). Auditory circuit in the Drosophila brain. Proc Natl Acad Sci USA 109: 2607-2612. (IF: 9.809, 5-Year IF: 10.727)
Lee PT, Lin HW, Chang YH, Fu TF, Dubnau J, Hirsh J, Lee T and Chiang AS*. (2011). Serotonin-mushroom body circuit modulating the formation of anesthesia-resistant memory in Drosophila.Proc Natl Acad Sci USA 108: 13794–13799. (IF: 9.412, 5-Year IF: 10.620)
Wu CL, Shih MF Lai SY, Yang HT, Turner GC, Chen L, Chiang AS*. (2011). Heterotypic gap junctions between two neurons in the Drosophila brain are critical for memory. Curr Biol 21: 848-854. (IF: 9.601, 5-Year IF: 10.174; this article has been reviewed in the “Dispatch” of the Current Biology21, R394-R395)
Chiang AS*, Lin CY, Chuang CC, Chang HM, Hsieh CH, Yeh CW, Shih CT, Wu JJ, Wang GT, Chen YC, Wu CC, Chen GY, Ching YT, Lee PC, Lin CY, Lin HH, Wu CC, Hsu HW, Huang YA, Chen JY, Chiang HJ, Lu CF, Ni RF, Yeh CY, Hwang JK. (2011). Three-dimensional reconstruction of brainwide wiring networks in Drosophila at single cell resolution. Curr Biol 21: 1-11. (Article, cover story) (IF: 9.601, 5-Year IF: 10.174;this article has been reviewed in the “Dispatch” of the Current Biology21, R19-R20)「紐約時報」專欄報導
Chang YC, Hung WT, Chang YC, Chang HC, Wu CL, Chiang AS, Jackson GR, Sang TK. (2011). Pathogenic VCP/TER94 alleles are dominant actives and contribute to neurodegeneration by altering cellular ATP level in a Drosophila IBMPFD Model. PLoS Genet 7: e1001288. (IF: 5.175, 5-Year IF: 5.858)
Tamura T, Horiuchi D, Chen YC, Sone M, Miyashita T, Saitoe M, Yoshimura N, Chiang AS and Okazawa H. (2010). Drosophila PQBP1 regulates expression of NMDA receptor subunit NR1 and stores a very short-term memory in projection neurons. J Neurosci 30: 14091–14101. (IF: 5.674, 5-Year IF: 6.335)
